After oral administration, the drug is well absorbed from the gastrointestinal tract. Therapeutic serum concentration of 50 ng / ml. Dimenhydrinate biotransformation in the liver and excreted by the kidneys completely within 24 hours. The half-life is about 3.5 hours. Small proviron steroid amounts can be displayed in breast milk.
- Sea and air sickness (prophylaxis).
- Prevention and treatment of symptoms of vestibular and labyrinth disorders (dizziness, nausea, vomiting, except for symptoms caused by anticancer therapy), Meniere’s disease.
- Hypersensitivity to dimenhydrinate and other ingredients;
- angle-closure glaucoma;
- Children under 6 years of age;
- lactation (breastfeeding);
- prostatic hyperplasia with clinical manifestations;
- acute exudative and bullous skin lesions.
Dimenhydrinate can not be taken simultaneously with cardiac glycosides; with drugs depressing the central nervous system and alcohol.
Precautions: administration of drugs that cause proviron steroid prolongation or hypokalemia, stenosis of the pylorus, liver disease, open-angle glaucoma, stenosing peptic ulcer, hyperthyroidism, diseases of the circulatory system, bradycardia, hypertension, urinary retention (including predisposition), obstruction bladder neck, bronchial asthma, hypomagnesemia, concomitant use of drugs with ototoxic effects, bismuth drugs, ibuprofen, analgesics, narcotic and psychotropic drugs.
Dosing and Administration
For the prevention of sea and air sickness pills taken 30 minutes before the planned trip, if necessary, with water: Adults and children over 14 years – 50-100 mg (1-2 tablets) Children from 6 to 14 years – 50 mg (1 tablet) dose may be repeated if necessary.
When vestibular disorders tablets administered by mouth, with or without food, if necessary with water: Adults and children over 14 years – 50-100 mg (1-2 tablets) 2-3 times / day (daily dose should not exceed 400 mg) . Children from 6 to 14 years – 50 mg (1 tablet) 3 times / day (daily dose should not exceed 150 mg).
From the blood and lymphatic system: rarely – hemolytic anemia. On the part proviron steroid of the central nervous system and sensory organs: very often – drowsiness, impaired concentration attention, dizziness; often – fatigue, weakness, tremor, anxiety, and irritability (especially in children), the development of paradoxical reactions (especially in children), disturbance of accommodation, reduction proviron in the twilight and color vision, increased intraocular pressure; rarely – headache, insomnia. On the part of the gastrointestinal tract:often – nausea, vomiting, diarrhea, constipation, abdominal pain, dry mouth; rarely – liver dysfunction, cholestatic jaundice; . very rare – loss of appetite On the part of the respiratory system: sometimes – dry mucous membranes of the nose and throat, thickening of bronchial secretions. Allergic reactions: seldom – allergic skin reactions (urticaria), photosensitivity; very rarely – exfoliative dermatitis, angioedema, bronchospasm. Other: . rare – dysuria With prolonged use may develop drug dependence.
Symptoms: The first symptoms of overdose can be observed 30 minutes – 2 hours after taking the drug, and occur mainly in the form of headaches, dryness of mucous membranes of the oropharynx, as well as dizziness, sleepiness and increasing fatigue. Later proviron steroid they may join itchy skin, increased skin blood vessels, dilated pupils and slow reaction of pupils to light, accommodation disturbances, nystagmus, decreased muscle tone and tendon reflexes, urinary retention, shortness of breath and slow, tachycardia, changes in blood pressure. The symptoms of depression: a violation of speech, orientation in space and time, confusion, ataxia, coma, may psychomotor agitation, hallucinations, convulsions (especially in infants). Severe cases may be fatal. online anabolic steroids pharmacy
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