proviron for sale

Sinestrol is a hormonal drug, chemical structure differs from steroid hormones estrogen, but the biological and therapeutic properties similar to them.
The therapeutic effect sinestrola proviron for sale identical action of drugs follicular hormone, both in terms of influence on the uterus and mammary glands, and in terms of impact cardiovascular, nervous system and the general state of the female body. Influenced sinestrola enhanced blood flow to the genitals, endometrial proliferation processes are activated. Sinestrol can cause bloating and breast enlargement due to the proliferation of the glandular tissue.
The drug has the property to eliminate vegetative-vascular disorders, occurring in women on the grounds of the depletion of ovarian function (menopause, post-castration).  Absorption is high, has the effect of “first pass” through the liver. Excretion by the kidneys; depending on the physiological state (single phase of the menstrual cycle), the age and other conditions of the elimination rate varies.

 

 

Indications for use:

 

  • conditions associated with inadequate ovarian function (primary and secondary amenorrhea, oligomenorrhea, dysmenorrhea);
  • hypoplasia of the genitals;
  • menopausal and post-castration disorder;
  • infertility; uterine inertia, prolonged pregnancy;
  • prostate cancer, breast cancer;

 

Contraindications:

Hypersensitivity to the drug.
Pregnancy; liver and kidney proviron for sale disease; breast disease, endometriosis, uterine bleeding unclear etiology, as well as in various forms of hyperestrogenism; diseases associated with increased blood clotting, malignant and benign novobrazovaniya genital and other organs of women (under 60 years).
pelvic inflammatory disease (oophoritis, endometritis), giperfollikulyarnaya stage of menopause, a tendency to uterine bleeding.

 

 

Dosage and administration:

The drug is administered in the form of oil solutions intramuscularly.

  • When gipogenitalizme, primary amenorrhea and underdevelopment of the uterus used for intramuscular injection of 1-2 mg daily for 4-6 weeks or more. In the presence of the effect then appoint progesterone or pregnin within 6-8 days In secondary amenorrhea appoint 1-2 mg Sinestrola for 15-20 days, then for 6-8 days appoint progesterone or pregnin at the indicated dose;
  • When oligomenorrhea – intramuscular injection of 1 mg every day or every other day for the first half of the intermenstrual period;
  • With infertility on the basis of uterine underdevelopment – by 1 mg intramuscularly in the first 7-8 days after menstruation;
  • When menopausal disorders appoint 0,5-1mg. The duration of treatment is individualized;
  • When prostate cancer is administered daily in 2 ml 2% solution Sinestrola (0,04g) for 30 days. During the year, 2-3 courses for 20 days with an interval of 2-3 months.
  • When prostate cancer is administered intramuscularly daily 4.3 ml of 2% solution Sinestrola (0,06-0,08g) for 2 months, followed by a 2% solution 0,5-1ml day intramuscularly. The total dose and duration of treatment depend on the changes in the prostate gland, the presence or absence of metastases, the general state and the degree of feminization;
  • In breast cancer in women over 60 years of use 2% Sinestrola solution. Administered daily starting at 1 ml per day, then the daily proviron for sale dose gradually increased to 5 ml. By careful observation establish the optimal dose to be administered for a long time.

 

In the treatment of malignant tumors:

  • the highest single-dose of 0,06g (Zml 2% solution);
  • the highest daily dose 0.1 g (5 ml 2% solution).

 

 

Side effect:

Nausea, vomiting, dizziness, rash, swelling of the eyelids, erythropenia.
With prolonged use: for men – feminization (decreased sexual function, swelling and pigmentation of the nipples, testicles decrease in size); women – hardening of the ovaries, the violation of sodium exchange (peripheral edema), metrorrhagia.

 

Cautions
use of the drug should only be performed by the attending physician, under its control after an accurate diagnosis. Before use, the drug should be heated to 30-40 ° C. In the case of deposition of crystals heated in a boiling water bath until their dissolution.

 

Interaction with other drugs:

Antiestrogen agent (klomifentsitrat et al.), Used to treat infertility, capable of blocking the estrogen receptors and reduce the effects of estrogen.
Folic acid and thyroid drugs enhance the effect sinestrola.
Side effects sinestrola decrease under the influence of progestins (progestogens), which serves as the basis for the joint appointment sinestrola with progestin drugs (pregnin, progesterone, etc.). Sinestrol enhances the effect of lipid-lowering agents, diuretics, antiarrhythmics, antihypertensive drugs, indirect anticoagulants.

 

Overdose
If high doses are possible liver proviron for sale toxicity; excessive proliferation of endometrial and uterine bleeding, peripheral edema, increase blood clotting. Marked feminization in men (decreased sexual function, swelling and pigmentation of the nipples, testicles decrease in size). Testosterone Cypionate in USA